Type 2 Diabetes Treatments

Type 2 Diabetes Treatments

A new generation of diabetes treatments has entered the market. In the United States and other Western countries, drug manufacturers have responded to an increasing number of people diagnosed with type 2 diabetes and are currently developing at least 100 new therapies. Learning to control blood sugar levels is critical to the health of people with type 2 diabetes. Fortunately, new diabetes drugs that have been developed will help people control their blood sugar and avoid type 2 diabetes that can lead to dangerous complications.

Here are some of the best medical treatments available for type-2 diabetes:



Sulfonylureas are one of the oldest drugs used to treat high blood sugar levels in type 2 diabetes. These drugs work by stimulating the pancreas to release more insulin, but only when islet beta cells still exist, they can succeed. Today, the second-generation version of these drugs helps people with type 2 diabetes control their blood sugar levels.

Sulfonylurea metformin was introduced in 1955. Since then, many other drugs have been developed in this category. The US Food and Drug Administration first approved drugs such as glibenclamide, glipizide and glimepiride in the 1980s.

Pioglitazone (Actos brand) was approved in 1999 and has undergone a series of reviews due to side effects. As a result, other restrictions have been added to the drug label. The drug’s generic drug was approved in 2012.



This category covers several drugs. They work by improving the way insulin is used in muscle and fat cells. They also reduce the production of glucose in the human liver.


SGLT-2 Inhibitors

A novel drug that regulates blood sugar in type 2 diabetes is called a sodium and glucose co-transport inhibitor. These drugs work by inhibiting certain types of proteins. These proteins increase the amount of glucose reabsorbed in the blood. The drug inhibits these proteins, and the kidneys remove glucose from the blood and excrete it in the urine. SGLT-2 inhibitors are recommended for use with diet and exercise to help normalize blood glucose levels in patients with type 2 diabetes.


DPP-4 Inhibitors

Other new diabetes drugs belong to different drug families because they have different roles in the human body. These drugs, called DPP-4 inhibitors, act by blocking the production of DPP-4, an enzyme that blocks the production of incretins. Gastrin is a hormone that, when necessary, helps increase glucose production and reduces liver production hormones when not needed. By blocking the enzyme, more incretins can be provided to regulate blood glucose levels and keep them within the normal range.


GLP-1 Drugs

The glucagon-like peptide receptor agonist drug (GLP-1) uses another method to control excess glucose. These FDA-approved diabetes drugs use several different mechanisms of action. They act on gastrointestinal peptides to increase insulin production. They also slow gastric emptying, reduce glucagon production after eating and reduce food intake. Together, these effects help to improve blood glucose regulation in patients with type 2 diabetes.


Combination Drugs

As time goes by, it may be more difficult to control blood sugar levels and other measures may be needed. For these patients, choosing a combination of drugs that use different biochemical methods to lower blood sugar may be a good choice, not only because they use different systems, but because they are more cost effective.

A drug called Glyxambil uses SGLT-2 inhibitors and DPP-4 inhibitors to prevent insulin from entering the kidneys and increasing glucose stored in the liver. Other drugs use SGLT-2 inhibitors in combination with the oldest diabetes drug, metformin, to improve blood sugar management. New drugs are being tested continuously to determine the combination that is most effective in controlling blood sugar levels.

Many of these drugs are not FDA-approved diabetes drugs and can be prescribed by doctors. There is no doubt that a new line of drugs will emerge in the next few years to help patients control type 2 diabetes. Whatever medical treatment your doctor takes, it is vital that you take steps to control your diet and lead a healthy lifestyle. Usually, these factors play a very important role in the disease. Try to exercise, even if you live a sedentary life, even adding moderate exercise to your daily activities can help.


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